产品货号:
Z21310
中文名称:
NANOS3抗体
英文名称:
Anti-NANOS3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-NANOS3 Antibody |
指标别名 | Nanos homolog 3,nanos homolog 3 (Drosophila),NANOS1L,NANOS3,NOS 3,NOS3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | NANOS3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Nanos3 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of the human Nanos3.The immunogen is located within the last 50 amino acids of Nanos3. |
计算分子量 | 19kDa |
成分 | Nanos3 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | Nanos3 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Nanos is a zinc-finger containing,RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates.In Drosophila,Nanos represses apoptosis during development to ensure proper germ-line development.Unlike Nanos1 whose expression in mice is dispensable,the Nanos2 and Nanos3 proteins are required for germ cell development.Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females,while Nanos3-null PGCs are lost during the migration stage regardless of sex.Nanos2 and Nanos3 have distinct expression patterns during embryo development,suggesting that these two proteins do not have redundant functions.However,expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background.Nanos3 expression can not rescue Nanos2-null defects. |
Uniprot ID | P60323 |
基因名全称 | Nanos homolog 3 (Drosophila) |
蛋白名全称 | Nanos homolog 3 (Drosophila) |
推荐稀释比 | Nanos3 antibody can be used for detection of Nanos3 by Western blot at 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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